RIX4414 (Rotarix™): a live attenuated human rotavirus vaccine

RIX4414 (Rotarix): a live attenuated human rotavirus vaccine.

report. New York: Oxford University; 2005. 4. Fortes Filho JB, Barros CK, daCostaMC, ProcianoyRS. Results of a program for the prevention of blindness caused by retinopathy of prematurity in southern Brazil. J Pediatr (Rio J). 2007;83:209-16. 5. Gilbert C, Fielder F, Gordillo L, Quinn G, Semiglia R, Visintin P, et al. Characteristics of infants with severe retinopathy of prematurity in countrie...

Rotarix (RIX4414): an oral human rotavirus vaccine.

Rotavirus is the most common cause of severe gastroenteritis in children younger than 3 years of age worldwide. New rotavirus vaccine candidates were required to confer early protection against the most common rotavirus serotypes and to be well tolerated and not associated with intussusception. RIX4414 is a human-attenuated G1(P8) oral rotavirus vaccine administered in two doses at approximatel...

Safety, immunogenicity, and protective efficacy of two doses of RIX4414 live attenuated human rotavirus vaccine in healthy Brazilian infants

Objective: To determine the safety, immunogenicity and efficacy of two doses of rotavirus vaccine in healthy Brazilian infants. Methods: A randomized, multicenter, double-blind, placebo-controlled trial was conducted in Brazil, Mexico and Venezuela. Infants received two oral doses of vaccine or placebo at 2 and 4 months of age, concurrently with routine immunizations, except for oral poliomyeli...

A review of prophylactic measure against brucellosis in human with a live attenuated vaccine

Development of a New Live Attenuated Mumps Virus Vaccine in Human Deploid Cells